NTA is a unique particle visualization technique that enables researchers to study the behavior of particles and molecules over time. In addition to the Zetasizer Nano, the lab at QMUL encompasses a range of Malvern technology, including Mastersizer 2000 laser diffraction particle sizing and NanoSight Nanoparticle Tracking Analysis (NTA). They measure size and microrheology using dynamic light scattering zeta potential and electrophoretic mobility using electrophoretic light scattering and molecular weight using static light scattering.
Malvern Instruments Worldwide Sales and service centres in over. Zetasizer Nano systems incorporate combinations of a particle size analyzer, zeta potential analyzer, molecular weight analyzer, protein mobility and microrheology measurements. Table 1: Size, molecular weight and zeta potential cells available with the Zetasizer range. “As part of the multi-disciplinary lab at QMUL, materials and biomaterials research groups throughout the university, from engineers and chemists through to biologists and physicists, are benefiting from access to analysis using the Zetasizer Nano,” she said. Dr Krystelle Mafina, Experimental Officer in Materials Characterization, handles all training for the instrumentation and services that allows the students to work correctly on the systems. The Zetasizer Nano used in this work is one of a wide range of characterization systems available in the multi-disciplinary lab at the School of Engineering and Materials Science at QMUL. The Zetasizer Nano has reliably delivered a substantial portion of this data and continues to help drive our research.” “As molecular size and charge define the parameters of these experiments, robust multivariate molecular analysis forms the bedrock of our research. “Precise in vitro recreation of the complex biological environments is appealing for applications within drug screening, biological studies and tissue engineering,” said Michal Lipka, PhD student from Dr Alvaro Mata’s research group. As the sample concentration is increased, both the amplitude and the apparent Z average size are decreased, indicative of the effects of multiple scattering. These measurements are crucial to developing bespoke cell culture platforms for the production of specific biologically significant hydrogel.īy creating hydrogel structures based on the charge of target biomolecules, researchers at QMUL aim to develop a fabrication process for advanced cell cultures that accurately represents scenarios within healthy or diseased tissue. a 200 nm latex standard, measured in the center of the sample cell with a Malvern Zetasizer Nano system. The Zetasizer Nano’s high performance electrophoretic light scattering capabilities are allowing researchers to better understand the nature of the electrostatic interactions between proteins and peptides. For further details of the Zetasizer Nano visit at the School of Engineering and Materials Science, Queen Mary University London (QMUL), are using a Malvern Instruments Zetasizer Nano to provide particle size and charge data that is being used in the development of innovative hydrogel matrices for 3D cell culture. It is also suitable for use with samples in aqueous media in either glass or disposable polystyrene cuvettes and requires as little as 0.7 ml sample. The cell's excellent chemical compatibility means that it can accommodate a wide variety of dispersants. PALS technology is used to ensure accurate results, and size measurements can be performed in the same cell without changing the sample. The dip cell simply clicks into place for immediate use. The new dip cell extends the range of sample types that can be included for zeta potential measurement, enabling analysis of materials in non-aqueous dispersants. Malvern Instruments has introduced a new dip cell for the Zetasizer Nano, the company's pioneering three-in-one system for particle size, zeta potential and molecular weight measurement of molecules and nano-sized particles. Original Press Release: New Dip Cell for Malvern's Zetasizer Nano Dip cell also suits use with samples in aqueous media, in glass, or disposable polystyrene cuvettes. PALS technology provides accurate results, and size measurements can be performed in same cell without changing sample. Dip cell extends range of sample types that can be included for zeta potential measurement. Dip cell combines with company's Zetasizer Nano three-in-one system for particle size, zeta potential, and molecular weight measurement of molecules and nano-sized particles.